PhD scholarship in structural biology at the Leibniz Research Institute for

PhD Fellowship in Structural Biology: The Leibniz Research Institute for Molecular Pharmacology (FMP) in Berlin offers a DFG-funded PhD position in cryo-EM and structural biology within the junior research group “Structure and Mechanism of Microbiome-Related Diseases” led by Dr. Daniel Roderer. This position offers an exciting opportunity to investigate the molecular mechanisms of microbiome-related carcinogenesis.

PhD scholarship for cryo-EM and structural biology at the Leibniz Research Institute for Molecular Pharmacology (FMP)

Designation

PhD position in Cryo-EM and Structural Biology (f/m/d)

Research area

• Molecular mechanism of microbiome-related carcinogenesis
• Cryogenic electron microscopy (cryo-EM)
• Structural biology
• Protein biochemistry
• biophysics

Location

Leibniz Research Institute for Molecular Pharmacology (FMP), Berlin, Germany

Authorization/Qualification

• Training: Master’s degree in Biochemistry, biophysics, chemistry, physics or a related field with very good grades.
• Experience: Solid experience in protein biochemistry or electron microscopy. Previous knowledge in structural biology (cryo-EM and/or X-ray crystallography) is an advantage.
• skills: High motivation, conscientious working style, ability to work in a team and the desire to achieve outstanding achievements in science. Fluent English is required; knowledge of German is not required.

Job description

The successful candidate will investigate the molecular mechanisms of binding of the autotransporter adhesin of Fusobacterium nucleatum to human target cells in the junior research group of Dr. Daniel Roderer. The project includes:

• Analysis of complexes between bacterial adhesins and human cell surface receptors.
• By using cryogenic electron microscopy (cryo-EM) and cryo-tomography (cryo-ET), a near atomic resolution of these interactions is achieved both in vitro and in cellular environments.

The position is initially limited to three years, with the possibility of an extension. The remuneration is based on the collective agreement for the public service (TVöD Bund), the position corresponds to 65% full-time employment.

Application

Interested applicants should submit the following documents in a single PDF file:

• Motivational letter
• CV
• Bachelor and Master certificates
• A 1-page presentation of research experience and interests
• Contact details of at least two references

Please send your application to Dr. Daniel Roderer at roderer@fmp-berlin.de by 31 August 2024.

For further information please contact Dr. Daniel Roderer or view the project-related preprint: Project Preprint.

We welcome applications from all people regardless of gender, age, ethnic origin or religion and are particularly pleased to receive applications from severely disabled people, who will be given priority if they have the same qualifications.

Deadline for application

31 August 2024

We look forward to receiving your application!

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